ACR-EULAR 2011 Defnition of Remission RA disease activity states defned by EULAR 2019 Disease activity states Remission ACR-EULAR remission defnition (Boolean or index based) Low disease activity state according to any of the validated composite Low disease activity disease activity measures that include joint counts Respective disease activity state according to any of the validated Moderate, high disease activity composite disease activity measures that include joint counts For clinical trials For clinical practice • Boolean • Boolean - SJC, TJC, PtGA, CRP all ≤1 - SJC, TJC, PtGA all ≤1 • Index-based • Index-based - SDAI ≤3.3 - CDAI ≤2.8 - SDAI=SJC+TJC+PhGA+PtGA+ CRP (mg/dl) - CDAI=SJC+TJC+PhGA+PtGA Ref: Felson D. Ann Rheum Dis 2011;70;404-13. Ref: Smolen J. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2019 update. 10.1136/annrheumdis-2019-216655 10
RkJQdWJsaXNoZXIy MjgzNzA=