Psoriatic arthritis (PsA) - Assessment of Disease Activity PsA is a multifaceted heterogeneous disease, involving the following domains: joints, entheses, dactylitis, axial skeleton, and skin & nails. The treatment target is considered clinical remission or, alternatively, low disease activity. Validated measures of musculoskeletal and skin disease activity should be used in clinical practice to guide treatment decisions. ref: Gossec L, Baraliakos X, Kerschbaumer A, et al. Ann Rheum Dis 2020;79:700–712. Singh JA et al. Arthritis Rheumatol. 2019 Jan;71(1):5-32. To date, there is no consensus on the disease activity indices for use in clinical practice and on the defnition of remission in PsA. Domains-based disease assessment Articular disease: 66 swollen and 68 tender joint counts (SJC and TJC) Swollen Tender Swollen Tender Joints Joints Joints Joints Temporomandibular joint (0-2) (0-2) Sternoclavicular joints (0-2) (0-2) Acromioclavicular joints (0-2) (0-2) Glenohumeral(s) (0-2) (0-2) Elbow(s) (0-2) (0-2) Wrist(s) (0-2) (0-2) Metacarpal phalangeal joints (0-10) (0-10) Finger Proximal interphalangeal joints (0-10) (0-10) Finger Distal interphalangeal joints (0-8) (0-8) Hip(s) NA (0-2) Knee(s) (0-2) (0-2) Ankle(s) (0-2) (0-2) Tarsus/Midfoot(feet) (0-2) (0-2) Metatarsal phalangeal joints (0-10) (0-10) Toe PIP(s) (0-10) (0-10) Total joint counts (0-66) (0-68) Ref: Duarte-García A et al. J Rheumatol 2019;46:996–1005. 11
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