Assessment of Disease

Non-articular musculoskeletal disease Enthesitis: LEI was developed as a measure for enthesitis in PsA. LEI evaluates 6 entheseal sites for presence or absence of tenderness when putting pressure (4Kg - enough to blanch the nail of the examiner): • bilateral lateral epicondyles • medial femoral condyles • Achilles tendon insertions Overall score range of 0–6. Higher count represents greater enthesitis burden. ref: Healy PJ, Helliwell PS. Arthritis Rheum 2008;59:686–91. Mease PJ. Arthritis Care Res 2011;63(S11):S64–S85. Leeds enthesitis index (LEI) Leed Enthesis Index - Lateral epicondyle (L,R) Leed Enthesis Index Medial femoral condyle (L,R) Leed Enthesis Index Achilles tendon insertion (L,R) 12

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