Minimal disease activity (MDA) criteria The criteria state that a patient is in MDA if they fulfll 5 of 7 of the following criteria: • Tender joint count (TJC) ≤1 • Swollen joint count (SJC) ≤1 • PASI ≤1 or BSA ≤3 • Patient pain VAS ≤15 • PGA VAS ≤20 • HAQ ≤0.5 • Tender entheseal points ≤1 Very low disease activity (VLDA) defned as a patient meeting all seven of the above criteria. Ref: Coates LC, Fransen J, Helliwell PS. Ann Rheum Dis 2010;69(1): 48–53. Psoriatic arthritis response criteria (PsARC) • PsARC are used in the assessment and monitoring of PsA in clinical trials • PsARC consists of four components: 68 TJC, 66 SJC, patient and physician global disease assessment • PsARC requires improvement in two factors (with at least one being a joint score), with worsening in none, of the previous four factors Ref: Mease PJ, et al. Arthritis Rheum 2005;52:3279–89. Defnition of remission in PsA According to 2017 update of recommendations by an international task force, DAPSA or MDA should be considered to defne the target of treatment in PsA (Ref: Smolen JS, Schols M, Braun J, et al. Ann Rheum Dis 2018;77:3–17). This recommendation is supported by the 2018 American College of Rheumatology/National Psoriasis Foundation Guideline for the Treatment of Psoriatic Arthritis (ref: Singh JA https://doi.org/10.1002/acr.23789). 19
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