The Ankylosing Spondylitis Disease Activity Score (ASDAS) ASDAS is a composite index to assess disease activity in axial SpA. ASDAS combines fve disease activity variables with only partial overlap, resulting in one single score with better validity, enhanced discriminative capacity, and improved sensitivity to change as compared to single-item variables. 1. How would you describe the overall level of a neck, back or hip pain you have had? None Very severe How long does your morning stiffness last from the time you wake up? 3. How active was your spondylitis on average during the last week? 4. How would you describe the overall level of pain/swelling in joints other than neck, back or hips you have had? 5. C-reactive protein (mg/L)? The ASDAS categorizes the disease activity as inactive, low, high, or very high. According to the 2016 ASAS-EULAR management recommendations for axial spondyloarthritis, ASDAS is considered a preferred measure for the assessment of disease activity applied in the treat-to-target strategy. ASDAS ≥2.1 warrants consideration of biologic therapy. 012345678910 2 or more Hours 012345678910 None Very severe 012345678910 Not active Very active 012345678910 ASDAS <1.3 • Inactive disease 1.2≤ ASDAS <3.5 • High disease activity ASDAS >3.5 • Very high disease activity 1.3≤ ASDAS <2.1 • Moderate disease activity 21
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